Agnosticism is a philosophical theory that holds that it is impossible to arrive at a knowledge of reality either because by its nature it is unknowable or because of limits of the human mind. In effect it denies that man by reason can come to knowledge o£ God and the truths of religion. Agnosticism in all its forms results in reducing man's knowledge to his own sense experience or to his subjective or emotional responses. The most general modern expression was set down by the English biologist Thomas Huxley in 1868, which can be said to hold that the human intellect is not able to come to a knowledge of anything immaterial, especially a knowledge of God and His nature, as well as the human soul. The correct doctrinal teaching was presented by Vatican Council I, reasserting the traditional claim of the Church as being in accord with reason.